ASYMMETRIC SYNTHESIS OF ALPHA AMINOPHOSPHONIC ACIDS .4. ASYMMETRIC-SYNTHESIS OF ENANTIOMERICALLY PURE PHOSPHONIC ANALOGS OF GLUTAMIC-ACID AND PROLINE

被引：58
|
作者：
GROTH, U [1 ]
RICHTER, L [1 ]
SCHOLLKOPF, U [1 ]
机构：
[1] UNIV GOTTINGEN,INST ORGAN CHEM,TAMMANNSTR 2,W-3400 GOTTINGEN,GERMANY
来源：
TETRAHEDRON | 1992年 / 48卷 / 01期
关键词：
D O I：
10.1016/S0040-4020(01)80584-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Michael addition of the metallated camphor derivatives 2 to vinylogous esters and subsequential hydrolysis afforded phosphonic analogues of glutamic acid. The enantiomerically pure lactam 6 was reduced by LiBH4/BF3.OEt2 to phosphoproline 7.
引用
收藏
页码：117 / 122
页数：6
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