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CHARACTERIZATION OF THE CYTOSKELETON IN HUMAN NORMAL AND OTOSCLEROTIC OSTEOBLAST-LIKE CELLS
被引:0
|作者:
ARENA, N
VENTI, G
BECCHETTI, E
BARONI, T
DONTI, E
PALUDETTI, G
BODO, M
机构:
[1] UNIV PERUGIA, DIPARTIMENTO MED SPERIMENTALE & SCI BIOCHIM, VIA GIOCHETTO, I-06100 PERUGIA, ITALY
[2] UNIV PERUGIA, IST CLIN MED, I-06100 PERUGIA, ITALY
[3] UNIV SASSARI, IST ISTOL & EMBRIOL GEN, I-07100 SASSARI, ITALY
[4] UNIV CATTOLICA SACRO CUORE, OTORINOLARINGOIATR CLIN, I-00168 ROME, ITALY
来源:
关键词:
CYTOSKELETON;
NORMAL OSTEOBLAST-LIKE CELLS;
OTOSCLEROTIC CELLS;
D O I:
暂无
中图分类号:
R602 [外科病理学、解剖学];
R32 [人体形态学];
学科分类号:
100101 ;
摘要:
The localization and distribution of some cytoskeletal protein components were studied by immunostaining methods in normal and otosclerotic osteoblast-like cells. The protein components investigated were microtubules (beta-tubulin), intermediate filaments (vimentin), microfilaments (actin and myosin) and structural proteins (alpha-actinin and fibronectin). Although the mechanism is not yet clear, the alterations observed in the pathological cells could well play a role in the expression of otosclerosis.
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页码:311 / 315
页数:5
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