SUSCEPTIBILITY OF SEVERAL SPECIES OF CANDIDA AND TORULOPSIS TO FLUCONAZOLE AND KETOCONAZOLE

被引：0
|
作者：
MALLIE, M [1 ]
MONTES, B [1 ]
REYNES, J [1 ]
BASTIDE, JM [1 ]
机构：
[1] CTR HOSP & REG UNIV MONTPELLIER,HOP GUI CHAULIAC,INFECT DIS CLIN A,F-34000 MONTPELLIER,FRANCE
来源：
DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH | 1990年 / 16卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The authors compared the in vitro antifungal activity of fluconazole, a new triazole antifungal agent, and ketoconazole, an imidazole derivative. The MIC values were determined against 50 strains of Candida albicans, 10 strains of C. guilliermondii, 10 strains of C. krusei, 10 strains of C. parapsilosis, 10 strains of C. pseudotropicalis, 10 strains of C. tropicalis and 15 strains of Torulopsis glabrata. The fungistatic activity was evaluated by the agar dilution method using BHl and casitone media after incubation for 48 h at 28-30-degrees-C. Both antifungal agents showed higher activity when tested on casitone medium; however, the G-MIC values for ketoconazole were lower than those for fluconazole.
引用
收藏
页码：509 / 513
页数：5
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