Vaccine hesitancy and refusal remain a major concern for healthcare professionals and policymakers. Hence, it is necessary to ascertain the underlying factors that promote or hinder the uptake of vaccines. Authorities and policy makers are experimenting with vaccine promotion messages to communities using loss and gain-framed messages. However, the effectiveness of message framing in influencing the intention to be vaccinated is unclear. Based on the Theory of Planned Behaviour (TPB), this study analysed the impact of individual attitude towards COVID-19 vaccination, direct and indirect social norms, perceived behavioural control and perceived threat towards South Indian millennials' intention to get vaccinated. The study also assessed the effect of framing vaccine communication messages with gain and loss framing. Data was collected from 228 Millennials from South India during the COVID-19 pandemic from September to October 2021 and analysed using PLS path modelling and Necessary Condition Analysis (NCA). The findings reveal that attitudes towards vaccination, perceived threat and indirect social norms positively impact millennials' intention to take up vaccines in both message frames. Further, independent sample t-test between the framing groups indicate that negative (loss framed message) leads to higher vaccination intention compared to positive (gain framed message). A loss-framed message is thus recommended for message framing to promote vaccine uptake among millennials. These findings provide useful information in understanding the impact of message framing on behavioural intentions, especially in the context of vaccine uptake intentions of Millennials in South India.
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Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
St Johns Res Inst, Div Mental Hlth & Neurosci, Bangalore, Karnataka, IndiaUniv Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
Ekstrand, Maria L.
Heylen, Elsa
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Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
Heylen, Elsa
Gandhi, Monica
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Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
Gandhi, Monica
Steward, Wayne T.
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Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
Steward, Wayne T.
Pereira, Matilda
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St Johns Res Inst, Div Mental Hlth & Neurosci, Bangalore, Karnataka, IndiaUniv Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
Pereira, Matilda
Srinivasan, Krishnamachari
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St Johns Res Inst, Div Mental Hlth & Neurosci, Bangalore, Karnataka, India
St Johns Med Coll, Dept Psychiat, Bangalore, Karnataka, IndiaUniv Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
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Kasturba Med Coll Mangalore, Med Program, Mangalore 575003, Karnataka, IndiaKasturba Med Coll Mangalore, Med Program, Mangalore 575003, Karnataka, India
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Natl Univ Med Sci, Army Med Coll, Dept Community Med, Rawalpindi, PakistanNatl Univ Med Sci, Army Med Coll, Dept Community Med, Rawalpindi, Pakistan
Malik, Asmara
Malik, Jahanzeb
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Rawalpindi Inst Cardiol, Dept Cardiol, Rawalpindi, PakistanNatl Univ Med Sci, Army Med Coll, Dept Community Med, Rawalpindi, Pakistan
Malik, Jahanzeb
Ishaq, Uzma
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Fdn Univ Med Coll, Dept Hematol, Islamabad, PakistanNatl Univ Med Sci, Army Med Coll, Dept Community Med, Rawalpindi, Pakistan
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Andrian, Titus
Koppe, Laetitia
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Koppe, Laetitia
Novel, Etienne
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Novel, Etienne
Massat, Maeva
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Massat, Maeva
Barba, Christophe
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Barba, Christophe
Ioriatti, Donatella
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Ioriatti, Donatella
Barnel, Cecile
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Barnel, Cecile
Villar, Emmanuel
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Hop St Joseph St Luc, Dept Nephrol & Dialysis, Lyon, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Villar, Emmanuel
Luce, Mathilde
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Hop St Joseph St Luc, Dept Nephrol & Dialysis, Lyon, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Luce, Mathilde
Guerraoui, Abdallah
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Hop Lucien Hussel Vienne, CALYDIAL, Montee Docteur Chapuis, Vienne, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Guerraoui, Abdallah
Mezaache, Sarah
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Hop Bourg Bresse, Dept Nephrol & Dialysis, Bourg En Bresse, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Mezaache, Sarah
Kalbacher, Emilie
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Hosp Civils Lyon, Dept Nephrol & Dialysis, Hop Edouard Herriot, Lyon, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Kalbacher, Emilie
Tournebize, Corentin
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Hosp Civils Lyon, Dept Nephrol & Dialysis, Hop Edouard Herriot, Lyon, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Tournebize, Corentin
Fouque, Denis
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France
Fouque, Denis
Chalencon, Elodie
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Hosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, FranceHosp Civils Lyon, Dept Nephrol Dialysis & Nutr, Hop Lyon Sud, Pierre Benite, France