CHANGES OF CARBOHYDRATE-DEFICIENT TRANSFERRIN IN CHRONIC-ALCOHOLISM

被引:4
|
作者
KONIG, P [1 ]
NIEDERHOFER, H [1 ]
STEURER, H [1 ]
HALLER, R [1 ]
WOLFLE, R [1 ]
FRITZSCHE, H [1 ]
WEISS, P [1 ]
机构
[1] LANDESKRANKENHAUSES FELDKIRCH, ISOTOPENABT, FELDKIRCH, AUSTRIA
关键词
CARBOHYDRATE-DEFICIENT TRANSFERRIN; LIVER FUNCTION STUDIES; CHRONIC ALCOHOLISM; MONITORING ABSTINENCE;
D O I
10.1159/000119235
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Compared with other well established liver enzyme parameters, carbohydrate-deficient transferrin (CDT) offers a new method for the identification of chronic alcoholism. The dependence of CDT and alcoholism/abstinence was studied in 29 controls and 64 alcoholics (both groups comprising men and women). In contrast to the currently used parameters GOT, GPT, gammaGT, LDH and MCV, CDT measures chronic alcoholism exclusively. CDT is dependent on sex but not age. In chronic alcoholism its rate increases significantly, but drops quickly after a short time of abstinence. CDT variations may be a specific and sensitive indicator of alcoholism or abstinence and possibly the duration.
引用
收藏
页码:192 / 196
页数:5
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