CHANGES OF CARBOHYDRATE-DEFICIENT TRANSFERRIN IN CHRONIC-ALCOHOLISM

被引：4
|
作者：
KONIG, P [1 ]
NIEDERHOFER, H [1 ]
STEURER, H [1 ]
HALLER, R [1 ]
WOLFLE, R [1 ]
FRITZSCHE, H [1 ]
WEISS, P [1 ]
机构：
[1] LANDESKRANKENHAUSES FELDKIRCH, ISOTOPENABT, FELDKIRCH, AUSTRIA
来源：
NEUROPSYCHOBIOLOGY | 1995年 / 32卷 / 04期
关键词：
CARBOHYDRATE-DEFICIENT TRANSFERRIN; LIVER FUNCTION STUDIES; CHRONIC ALCOHOLISM; MONITORING ABSTINENCE;
D O I：
10.1159/000119235
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Compared with other well established liver enzyme parameters, carbohydrate-deficient transferrin (CDT) offers a new method for the identification of chronic alcoholism. The dependence of CDT and alcoholism/abstinence was studied in 29 controls and 64 alcoholics (both groups comprising men and women). In contrast to the currently used parameters GOT, GPT, gammaGT, LDH and MCV, CDT measures chronic alcoholism exclusively. CDT is dependent on sex but not age. In chronic alcoholism its rate increases significantly, but drops quickly after a short time of abstinence. CDT variations may be a specific and sensitive indicator of alcoholism or abstinence and possibly the duration.
引用
收藏
页码：192 / 196
页数：5
相关论文
共 50 条
  • [1] CARBOHYDRATE-DEFICIENT TRANSFERRIN - A VERY ATTRACTIVE BIOLOGICAL MARKER RELATED TO CHRONIC-ALCOHOLISM
    RENVERSEZ, JC
    ALZIEU, C
    VERNET, M
    ANNALES DE BIOLOGIE CLINIQUE, 1992, 50 (01) : 1 - 7
  • [2] CORRELATIONS BETWEEN ACETALDEHYDE-MODIFIED HEMOGLOBIN, CARBOHYDRATE-DEFICIENT TRANSFERRIN (CDT) AND HEMATOLOGICAL ABNORMALITIES IN CHRONIC-ALCOHOLISM
    WICKRAMASINGHE, SN
    CORRIDAN, B
    HASAN, R
    MARJOT, DH
    ALCOHOL AND ALCOHOLISM, 1994, 29 (04): : 415 - 423
  • [3] The analysis of carbohydrate-deficient transferrin, marker of chronic alcoholism, using capillary electrophoresis
    Wuyts, B
    Delanghe, JR
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2003, 41 (06) : 739 - 746
  • [4] Clinical correlations with carbohydrate-deficient transferrin levels in women with alcoholism
    Oslin, DW
    Pettinati, HM
    Luck, G
    Semwanga, A
    Cnaan, A
    O'Brien, CP
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1998, 22 (09) : 1981 - 1985
  • [5] Accuracy of carbohydrate-deficient transferrin as a biomarker of chronic alcohol abuse during treatment for alcoholism
    Suzuki, Tatsuya
    Eguchi, Akiko
    Shigefuku, Ryuta
    Nagao, Saeko
    Morikawa, Masayuki
    Sugimoto, Kazushi
    Iwasa, Motoh
    Takei, Yoshiyuki
    HEPATOLOGY RESEARCH, 2022, 52 (01) : 120 - 127
  • [6] Evaluation of the diagnostic utility of carbohydrate-deficient transferrin in chronic alcoholism Results from Southwest China
    Liang, Shan-Shan
    He, Ying
    Huang, Zhi-Gang
    Jia, Cheng-Yao
    Gan, Wei
    MEDICINE, 2021, 100 (04)
  • [7] CARBOHYDRATE-DEFICIENT TRANSFERRIN - A NEW COPREDICTOR OF ALCOHOLISM RELATED POSTOPERATIVE COMPLICATIONS
    HEIL, T
    SPIES, C
    NEUMANN, T
    MULLER, C
    BRITISH JOURNAL OF ANAESTHESIA, 1993, 70 : 45 - 45
  • [8] Carbohydrate-deficient transferrin as compared to other markers of alcoholism: A systematic review
    Salaspuro, M
    ALCOHOL, 1999, 19 (03) : 261 - 271
  • [9] Vitreous humor carbohydrate-deficient transferrin concentrations in the postmortem diagnosis of alcoholism
    Osuna, E
    Pérez-Cárceles, MD
    Moreno, M
    Bedate, A
    Conejero, J
    Abenza, JM
    Martínez, P
    Luna, A
    FORENSIC SCIENCE INTERNATIONAL, 2000, 108 (03) : 205 - 213
  • [10] Carbohydrate-deficient transferrin in galactosaemia
    Stibler, H
    von Döbeln, U
    Kristiansson, B
    Guthenberg, C
    ACTA PAEDIATRICA, 1997, 86 (12) : 1377 - 1378
12345