A DOUBLE-BLIND-STUDY ON AZATHIOPRINE EFFICACY IN MULTIPLE-SCLEROSIS - FINAL REPORT

被引：37
|
作者：
MILANESE, C
LAMANTIA, L
SALMAGGI, A
EOLI, M
机构：
[1] Istituto Nazionale Neurologico C. Besta, Milan, I-20133, Via Celoria
来源：
JOURNAL OF NEUROLOGY | 1993年 / 240卷 / 05期
关键词：
MULTIPLE SCLEROSIS; AZATHIOPRINE;
D O I：
10.1007/BF00838165
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Forty patients, affected by multiple sclerosis with remitting-relapsing or progressive course, were included in a double blind study of treatment with azathioprine (2 mg/kg/day) lasting 3 years. The mean changes on the Expanded Disability Status Scale and in the survival analysis show a trend in favour of azathioprine both in slowing disease progression and reducing relapse frequency. These findings, repeatedly observed in similar trials, indicate that azathioprine should be used in the treatment of multiple sclerosis.
引用
收藏
页码：295 / 298
页数：4
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