COMPARISON OF CELL-CULTURE WITH AN AMPLIFIED ENZYME-IMMUNOASSAY FOR DIAGNOSING GENITAL HERPES-SIMPLEX INFECTION

被引：6
|
作者：
KUDESIA, G [1 ]
VANHEGAN, A [1 ]
WAKE, S [1 ]
VANHEGAN, RJ [1 ]
KINGHORN, GR [1 ]
机构：
[1] NO GEN HOSP,DEPT GENITOURINARY MED,SHEFFIELD S5 7AU,S YORKSHIRE,ENGLAND
来源：
JOURNAL OF CLINICAL PATHOLOGY | 1991年 / 44卷 / 09期
关键词：
D O I：
10.1136/jcp.44.9.778
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
An amplified enzyme immunoassay (EIA) for herpes simplex virus (Novo Nordisk) was compared with cell culture in 853 genital specimens from a genitourinary medicine clinic. The sensitivity of the EIA was 86% and its specificity 99.6%. The sensitivity increased to 94% for lesion swabs but decreased to 68% for cervical swabs. Sensitivity for urethral and vulval swabs was 83% and 82%, respectively. It is concluded that the EIA is specific and quick and easy to perform. It will be suitable for testing for genital herpes simplex infections in laboratories without access to local cell culture facilities.
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页码：778 / 780
页数：3
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