PRODUCTION OF MONOCLONAL-ANTIBODIES AGAINST THYROXINE

被引：0
|
作者：
DANILOVA, NP
KRUPINA, NV
MERTZ, MV
VASILOV, RG
机构：
来源：
BIOORGANICHESKAYA KHIMIYA | 1993年 / 19卷 / 07期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Spleen cells of BALB/c mouse immunized with the keyhole limpet haemocyanin and thyroxine conjugate were fused with P3-X63-Ag8.653 mouse myeloma cells to produce. Four monoclonal antibodies selected by indirect ELISA and partially characterized. One antibody, 1B7, chosen for immunoassay, was produced in mouse ascites fluid, purified and analyzed; it proved to belong to the IgG1 subclass. The cross-reactivity with triiodothyronine was less than 1%, the association constant was 3 . 10(9) M-1.
引用
收藏
页码：704 / 712
页数：9
相关论文
共 50 条
  • [41] MONOCLONAL-ANTIBODIES AGAINST ROTAVIRUSES
    GRUNERT, B
    STRECKERT, HJ
    WERCHAU, H
    ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIES A-MEDICAL MICROBIOLOGY INFECTIOUS DISEASES VIROLOGY PARASITOLOGY, 1985, 260 (04): : 475 - 475
  • [42] MONOCLONAL-ANTIBODIES AGAINST DOXORUBICIN
    BALSARI, A
    ALZANI, R
    PARRELLO, D
    MORELLI, D
    TAGLIABUE, E
    GIANNI, L
    ISETTA, AM
    MENARD, S
    COLNAGHI, MI
    GHIONE, M
    INTERNATIONAL JOURNAL OF CANCER, 1988, 42 (05) : 798 - 802
  • [43] MONOCLONAL-ANTIBODIES AGAINST ZEINS
    BRINK, DE
    PRICE, SC
    MARTINEZ, C
    SEED SCIENCE AND TECHNOLOGY, 1989, 17 (01) : 1 - 6
  • [44] MONOCLONAL-ANTIBODIES AGAINST MYCOBACTERIA
    STAER, AF
    BENNEDSEN, J
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1983, 18 (01) : 73 - 73
  • [45] MONOCLONAL-ANTIBODIES AGAINST OVALBUMIN
    BJERCKE, RJ
    HALE, PM
    MERCER, WD
    MCGUIRE, WL
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 99 (02) : 550 - 556
  • [46] MONOCLONAL-ANTIBODIES AGAINST LEISHMANIA
    INFANTE, RB
    LYNCH, NR
    MALAVE, C
    CONVIT, J
    ACTA CIENTIFICA VENEZOLANA, 1986, 37 (03): : 334 - 335
  • [47] MONOCLONAL-ANTIBODIES AGAINST HEMOGLOBINS
    HECHT, T
    WINKLER, K
    GAIDULIS, L
    BLUME, K
    BLUT, 1982, 45 (03): : 208 - 208
  • [48] MONOCLONAL-ANTIBODIES AGAINST MICROORGANISMS
    LEHNER, T
    CURRENT OPINION IN IMMUNOLOGY, 1989, 1 (03) : 462 - 466
  • [49] PRODUCTION OF MONOCLONAL-ANTIBODIES AND APPLICATION OF MONOSPECIFIC AND MONOCLONAL-ANTIBODIES IN IMMUNOCHEMICAL ANALYSIS
    KOMISSARENKO, SV
    FIZIOLOGICHESKII ZHURNAL, 1982, 28 (04): : 477 - 485
  • [50] PRODUCTION OF MONOCLONAL-ANTIBODIES AGAINST L-HISTIDINE DECARBOXYLASE
    POLLARD, H
    PACHOT, I
    SCHWARTZ, JC
    LANGE, M
    LEGRAIN, P
    BUTTIN, G
    COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES, 1983, 297 (12): : 553 - 556
12345