THE INHIBITION CONSTANTS FOR BLOCKADE OF [H-3] 5-HYDROXYTRYPTAMINE REUPTAKE ARE VARIABLE AND DEPENDENT ON TISSUE CONCENTRATION

被引：0
|
作者：
CHEETHAM, SC [1 ]
VIGGERS, JA [1 ]
SLATER, NA [1 ]
HEAL, DJ [1 ]
BUCKETT, WR [1 ]
机构：
[1] BOOTS PHARMACEUT RES DEPT,NOTTINGHAM NG2 3AA,ENGLAND
来源：
EUROPEAN JOURNAL OF PHARMACOLOGY | 1990年 / 183卷 / 05期
关键词：
D O I：
10.1016/0014-2999(90)92243-C
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1901 / 1902
页数：2
相关论文
共 50 条
  • [31] TRICHLOROETHYLENE INHIBITS UPTAKE OF H-3 5-HYDROXYTRYPTAMINE BUT NOT UPTAKE OF H-3 ZIMELDINE OR H-3 PROPRANOLOL IN ISOLATED PERFUSED RAT LUNGS
    HEDE, AR
    BERGLUND, BG
    POST, C
    PHARMACOLOGY & TOXICOLOGY, 1987, 61 (02): : 138 - 141
  • [32] INHIBITION OF 5-HYDROXYTRYPTAMINE REUPTAKE BY AMITRIPTYLINE AND ZIMELIDINE AND ITS RELATIONSHIP TO THEIR THERAPEUTIC ACTION
    COPPEN, A
    RAO, VAR
    SWADE, C
    WOOD, K
    PSYCHOPHARMACOLOGY, 1979, 63 (02) : 125 - 129
  • [33] IFENPRODIL INHIBITION OF THE 5-HYDROXYTRYPTAMINE(3) RECEPTOR
    MCCOOL, BA
    LOVINGER, DM
    NEUROPHARMACOLOGY, 1995, 34 (06) : 621 - 629
  • [34] Alniditan, a new 5-hydroxytryptamine(1D) agonist and migraine-abortive agent: Ligand-binding properties of human 5-hydroxytryptamine(1D alpha), human 5-hydroxytryptamine(1D beta), and calf 5-hydroxytryptamine(1D) receptors investigated with [H-3]5-hydroxytryptamine and [H-3]Alniditan
    Leysen, JE
    Gommeren, W
    Heylen, L
    Luyten, WHML
    VandeWeyer, I
    Vanhoenacker, P
    Haegeman, G
    Schotte, A
    VanGompel, P
    Wouters, R
    Lesage, AS
    MOLECULAR PHARMACOLOGY, 1996, 50 (06) : 1567 - 1580
  • [35] EFFECT OF ETHANOL ON UPTAKE BY RAT-BRAIN SYNAPTOSOMES OF [H-3]DL-NOREPINEPHRINE, [H-3]5-HYDROXYTRYPTAMINE, [H-3]GABA AND [H-3]GLUTAMATE
    ROACH, MK
    DAVIS, DL
    PENNINGTON, W
    NORDYKE, E
    LIFE SCIENCE PART 1 PHYSIOLOGY & PHARMACOLOGY, 1973, 12 (10): : 433 - 441
  • [36] REGULATION OF [H-3]5-HYDROXYTRYPTAMINE RELEASE FROM RAT-BRAIN SLICES
    FARNEBO, LO
    HAMBERGER, B
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 1974, 26 (08) : 642 - 643
  • [37] IDENTIFICATION OF MULTIPLE BINDING-SITES FOR [H-3] 5-HYDROXYTRYPTAMINE IN THE RAT CNS
    BLURTON, PA
    WOOD, MD
    JOURNAL OF NEUROCHEMISTRY, 1986, 46 (05) : 1392 - 1398
  • [38] NECESSITY OF ASCORBIC-ACID IN THE RADIOLIGAND BINDING ASSAY FOR [H-3] 5-HYDROXYTRYPTAMINE
    ANDRESEN, JW
    SHIH, JC
    NEUROPHARMACOLOGY, 1986, 25 (08) : 869 - 875
  • [39] OPIOID EFFECTS ON SPINAL [H-3] 5-HYDROXYTRYPTAMINE RELEASE ARE NOT RELATED TO THEIR ANTINOCICEPTIVE ACTION
    MONROE, PJ
    KRADEL, BK
    SMITH, DL
    SMITH, DJ
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1995, 272 (01) : 51 - 56
  • [40] METITEPINE DISTINGUISHES 2 RECEPTORS MEDIATING INHIBITION OF [H-3] 5-HYDROXYTRYPTAMINE RELEASE IN GUINEA-PIG HIPPOCAMPUS
    WILKINSON, LO
    MIDDLEMISS, DN
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1992, 345 (06) : 696 - 699
12345