A QSAR INVESTIGATION OF DIHYDROFOLATE-REDUCTASE INHIBITION BY BAKER TRIAZINES BASED UPON MOLECULAR SHAPE-ANALYSIS

被引：221

|

作者：

HOPFINGER, AJ

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1980年 / 102卷 / 24期

关键词：

D O I：

10.1021/ja00544a005

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

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页码：7196 / 7206

页数：11

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[21] RAPID ANALYSIS OF THE CONSEQUENCES OF DIHYDROFOLATE-REDUCTASE (DHFR) INHIBITION BY METHOTREXATE (MTX) OR TRIMETREXATE (TMQ) IN L1210 CELLS
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[22] STEREOCHEMISTRY OF DIHYDROFOLATE-REDUCTASE INHIBITOR ANTI-TUMOR AGENTS - MOLECULAR-STRUCTURE OF BAKER ANTIFOL (NSC-139105, TRIAZINATE) AND INSOLUBLE BAKER ANTIFOL (NSC-113423)
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[23] INTRINSIC MUTAGENICITY OF POLYCYCLIC AROMATIC-HYDROCARBONS - A QUANTITATIVE STRUCTURE ACTIVITY STUDY BASED UPON MOLECULAR SHAPE-ANALYSIS
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[24] TIME-DEPENDENT MOLECULAR SHAPE-ANALYSIS - AN EXTENDED APPROACH TO GENERATING 3D-QSAR MODELS
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[25] CORRELATION ANALYSIS OF BAKERS STUDIES ON ENZYME INHIBITION .1. GUANINE DEAMINASE, XANTHINE-OXIDASE, DIHYDROFOLATE-REDUCTASE, AND COMPLEMENT
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[26] ANALYSIS OF HYDRIDE TRANSFER AND COFACTOR FLUORESCENCE DECAY IN MUTANTS OF DIHYDROFOLATE-REDUCTASE - POSSIBLE EVIDENCE FOR PARTICIPATION OF ENZYME MOLECULAR MOTIONS IN CATALYSIS
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[27] CONFORMATIONAL-ANALYSIS OF LIPOPHILIC ANTIFOLATES - CRYSTAL AND MOLECULAR-STRUCTURES OF 3 S-TRIAZINE DIHYDROFOLATE-REDUCTASE INHIBITORS
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[28] DIHYDROFOLATE-REDUCTASE INHIBITION - A STUDY IN THE USE OF X-RAY CRYSTALLOGRAPHY, MOLECULAR GRAPHICS, AND QUANTITATIVE STRUCTURE-ACTIVITY RELATIONS IN DRUG DESIGN
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[29] INHIBITION OF HUMAN DIHYDROFOLATE-REDUCTASE BY 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1-(SUBSTITUTED-PHENYL)-S-TRIAZINES - A QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP ANALYSIS
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[30] A 3D-QSAR study of anticoccidial triazines using molecular shape analysis (vol 35, pg 771, 1995)
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