THE EXCRETION OF URINARY GLYCOSAMINOGLYCANS BY FLUOROTIC RATS

被引：0
|
作者：
STANBURY, JB
EMBERY, G
机构：
[1] UNIV WALES COLL MED,SCH DENT,DEPT BASIC DENT SCI,HEATH PK,CARDIFF CF4 4XY,WALES
[2] UNIV LIVERPOOL,DEPT CLIN DENT SCI,LIVERPOOL L69 3BX,ENGLAND
来源：
FLUORIDE | 1993年 / 26卷 / 04期
关键词：
EXCRETION; FLUOROSIS; GLYCOSAMINOGLYCANS; RATS; URINE;
D O I：
暂无
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This study describes differences in excretion of sulphated glycoproteins, including glycosaminoglycans and possibly Tam-Horsfall like proteins, in the urine of fluorotic and control rats. Changes in molecular size of protein and covalently bound radiosulphate profiles together with differences in Alcian blue and Ponceau S staining of the electrophoretically separated molecular size fractions were evident in fluorotic urines. The findings highlight changes in connective tissues in fluorosis which manifest themselves as urinary metabolites.
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页码：247 / 256
页数：10
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