Large-Cell Neuroendocrine Carcinoma of the Lung: An Aggressive Neuroendocrine Lung Cancer

被引：35

作者：

Fernandez, Felix G. ^{[1
]}

Battafarano, Richard J. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Surg, Div Cardiothorac Surg, St Louis, MO USA

来源：

SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY | 2006年 / 18卷 / 03期

关键词：

neuroendocrine spectrum; pulmonary tumors; large cell neuroendocrine carcinoma; non-small cell lung cancer;

D O I：

10.1053/j.semtcvs.2006.08.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Large cell neuroendocrine carcinoma (LCNEC) is part of the neuroendocrine spectrum of pulmonary tumors. This increasingly recognized tumor has been reported to have 5-year actuarial survival rates following resection that are worse than those described for other variants of non-small cell lung cancer (NSCLC). Therefore, debate has emerged regarding whether the tumors should be classified and treated as NSCLC or small-cell lung cancer. This article reviews the tumor characterization, biology, presentation and diagnosis, surgical therapy, results of therapy, and long term prognosis of patients with LCNEC. © 2006 Elsevier Inc. All rights reserved.

引用

页码：206 / 210

页数：5

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