THE FREQUENCY OF MOUSE SPLEEN DENDRITIC CELLS WHICH PRESENT ALLOANTIGENS OR OVALBUMIN TO PRIMED LYMPHOCYTE-T IS EQUAL

被引：1

作者：

GOODACRE, JA ^{[1
]}

JOHNSTONE, R ^{[1
]}

ATHERTON, MC ^{[1
]}

ROBINSON, JH ^{[1
]}

机构：

[1] NEWCASTLE UNIV, SCH PATHOL SCI, DIV IMMUNOL, Newcastle Upon Tyne, Tyne & Wear, ENGLAND

来源：

CELLULAR IMMUNOLOGY | 1990年 / 126卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0008-8749(90)90331-K

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have used limiting dilution analysis to compare the frequency of dendritic cells (DC) which present endogenous alloantigens with that which present an exogenous protein antigen to T lymphocytes. Spleen DC present alloantigens or ovalbumin to primed T lymphocytes with equal frequency, showing that DC are equipotent for presenting endogenous and exogenous antigens. Also, antigen-presenting cell (APC) frequencies among DC were compared with other APC populations. DC were enriched about 1000-fold for APC compared to unfractionated spleen cells. © 1990.

引用

页码：406 / 413

页数：8

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