INCIDENCE OF PSYCHOACTIVE CANNABINOIDS IN DRIVERS KILLED IN MOTOR-VEHICLE ACCIDENTS

被引：0

作者：

GEROSTAMOULOS, J ^{[1
]}

DRUMMER, OH ^{[1
]}

机构：

[1] MONASH UNIV, DEPT FORENS MED, S MELBOURNE, VIC 3205, AUSTRALIA

来源：

JOURNAL OF FORENSIC SCIENCES | 1993年 / 38卷 / 03期

关键词：

TOXICOLOGY; HPLC; PSYCHOACTIVE CANNABINOIDS; THC; 11-HYDROXY-THC; MARIJUANA;

D O I：

暂无

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A high performance liquid chromatography (HPLC) assay was developed for the psychoactive cannabinoids Delta-9-Tetrahydrocannabinol (THE) and 11-Hydroxy-THE (11-OH-THE) using electrochemical detection (ECD). A C8 bonded column was used and the mobile phase consisted of acetonitrile, methanol and 0.01 M sulphuric acid at a flow rate of 1.5 mL/min. The detection limits for both THE and 11-OH-THE were 1.0 ng/mL. Preliminary screening of 193 drivers using an enzyme-multiplied immunoassay technique (EMIT) showed 21 tested positive on either blood, urine or both. Of these subjects 13 were confirmed as positive by the HPLC/ECD method in blood. Blood concentrations for THE ranged from 1.4 ng/mL up to 20 ng/mL and for 11-OH-THE 2.5 ng/mL up to 85 ng/mL.

引用

页码：649 / 656

页数：8

共 50 条

[41] THE DETERMINANTS OF MOTOR-VEHICLE ACCIDENTS - A SPECIFICATION ERROR ANALYSIS
LOEB, PD
[J]. LOGISTICS AND TRANSPORTATION REVIEW, 1988, 24 (01): : 33 - 48
[42] FATAL MOTOR-VEHICLE ACCIDENTS INVOLVING AUSTRALIAN CHILDREN
PEARN, JH
[J]. AUSTRALIAN PAEDIATRIC JOURNAL, 1978, 14 (02): : 74 - 77
[43] POSTTRAUMATIC-STRESS-DISORDER AND MOTOR-VEHICLE ACCIDENTS
HICKLING, EJ
BLANCHARD, EB
[J]. JOURNAL OF ANXIETY DISORDERS, 1992, 6 (03) : 285 - 291
[44] PENETRATING OCULAR INJURIES SECONDARY TO MOTOR-VEHICLE ACCIDENTS
MURPHY, ML
NANDA, SK
MIELER, WF
[J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1992, 33 (04) : 1312 - 1312
[45] MOTOR-VEHICLE ACCIDENTS - THE FAMILY PRACTITIONERS ROLE IN THEIR MANAGEMENT
KNIGHT, PR
THOMAS, EJ
[J]. CANADIAN FAMILY PHYSICIAN, 1980, 26 (OCT) : 1327 - 1332
[46] MOTOR-VEHICLE ACCIDENTS - AN AVOIDABLE CAUSE OF INJURY IN CHILDHOOD
DICKERSON, DA
BASS, DH
RODRIQUES, AF
[J]. SOUTH AFRICAN MEDICAL JOURNAL, 1990, 78 (07): : 431 - 431
[47] IMPALEMENT INJURIES TO THE THORAX AS A RESULT OF MOTOR-VEHICLE ACCIDENTS
HYDE, MR
SCHMIDT, CA
JACOBSON, JG
VYHMEISTER, EE
LAUGHLIN, LL
[J]. ANNALS OF THORACIC SURGERY, 1987, 43 (02): : 189 - 190
[48] MOTOR-VEHICLE ACCIDENTS AND NUCLEAR UTILITY WORKERS - REPLY
LANES, SF
DREYER, NA
ROTHMAN, KJ
LOUGHLIN, JE
[J]. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1989, 31 (09) : 799 - 799
[49] THE RELATIONSHIP OF SMOKING TO MOTOR-VEHICLE ACCIDENTS AND TRAFFIC VIOLATIONS
DIFRANZA, JR
WINTERS, TH
GOLDBERG, RJ
CIRILLO, L
BILIOURIS, T
[J]. NEW YORK STATE JOURNAL OF MEDICINE, 1986, 86 (09) : 464 - 467
[50] POSTTRAUMATIC STRESS DISORDER IN VICTIMS OF MOTOR-VEHICLE ACCIDENTS
BURSTEIN, A
[J]. HOSPITAL AND COMMUNITY PSYCHIATRY, 1989, 40 (03): : 295 - 297

← 1 2 3 4 5 →