POTENTIAL OF MACHINE-VISION LIGHT-MICROSCOPY IN TOXICOLOGIC PATHOLOGY

被引：13
|
作者：
TAYLOR, DL
DEBIASIO, R
LAROCCA, G
PANE, D
POST, P
KOLEGA, J
GIULIANO, K
BURTON, K
GOUGH, B
DOW, A
YU, J
WAGGONER, AS
FARKAS, DL
机构：
[1] Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213
来源：
TOXICOLOGIC PATHOLOGY | 1994年 / 22卷 / 02期
关键词：
FLUORESCENCE; 3-DIMENSIONAL MICROSCOPY; VIDEO-ENHANCED CONTRAST; IN-SITU HYBRIDIZATION; IMMUNOFLUORESCENCE; FLUORESCENT ANALOGS;
D O I：
10.1177/019262339402200208
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Major developments in machine-vision light microscopy and in reagent chemistry have led to a renaissance and revolution in the use of the light microscope in biology, biotechnology, and medicine. The potential use of this technology in the field of toxicologic pathology is discussed. It is suggested that a combination of investigating living cells and tissues and fixed samples using the new technologies will lead to understanding mechanisms of toxicity. Examples of the use of the methods in basic cell biology and medicine are presented.
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页码：145 / 159
页数：15
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