Pathogenesis of HIV-1

被引：1
|
作者：
Metzner, Karin J. [1 ]
机构：
[1] Univ Spital Zurich, Klin Infekt Krankheiten & Spitalhyg, U RAE 70,Ramistr 100, CH-8091 Zurich, Switzerland
来源：
THERAPEUTISCHE UMSCHAU | 2014年 / 71卷 / 08期
关键词：
D O I：
10.1024/0040-5930/a000536
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The human immunodeficiency virus type 1 (HIV-1) establishes a chronic, lifelong infection finally leading to the acquired immunodeficiency syndrome (AIDS), which is characterized by the onset of opportunistic infections and tumors. The natural course of HIV-1 infections is very variable and depends on the virus and its replication competence as well as the host. This review summarizes our current knowledge on HIV-1 and host factors influencing the pathogenesis of HIV-1.
引用
收藏
页码：443 / 450
页数：8
相关论文
共 50 条
  • [41] Therapeutic perspectives in HIV-1 infection from recent advances in HIV-1 pathogenesis: it is time to move on
    Rizzardi, GP
    Pantaleo, G
    [J]. JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 1999, 13 (03): : 151 - 157
  • [42] Use of Human Mucosal Tissue to Study HIV-1 Pathogenesis and Evaluate HIV-1 Prevention Modalities
    Dezzutti, Charlene S.
    Hladik, Florian
    [J]. CURRENT HIV/AIDS REPORTS, 2013, 10 (01) : 12 - 20
  • [43] Antibody to HIV-1 Tat protein, a key molecule in HIV-1 pathogenesis. A brief review
    Re, MC
    Gibellini, D
    Vitone, F
    La Placa, M
    [J]. MICROBIOLOGICA, 2001, 24 (02): : 197 - 205
  • [44] Use of Human Mucosal Tissue to Study HIV-1 Pathogenesis and Evaluate HIV-1 Prevention Modalities
    Charlene S. Dezzutti
    Florian Hladik
    [J]. Current HIV/AIDS Reports, 2013, 10 : 12 - 20
  • [45] HIV-Associated Pathogenesis: The Role of HIV-1 Nef Gene
    Xiaoning Xu~(1)
    [J]. 首都医科大学学报, 2006, (02) : 198 - 202
  • [46] The role of monocytes and macrophages in the pathogenesis of HIV-1 infection
    Kedzierska, K
    Crowe, SM
    [J]. CURRENT MEDICINAL CHEMISTRY, 2002, 9 (21) : 1893 - 1903
  • [47] Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
    Oliver T. Fackler
    Andres Alcover
    Olivier Schwartz
    [J]. Nature Reviews Immunology, 2007, 7 : 310 - 317
  • [48] Is the nef protein of HIV-1 required for pathogenesis? Response
    Deacon, NJ
    McPhee, DA
    Crowe, S
    Mills, J
    Learmont, J
    [J]. TRENDS IN MICROBIOLOGY, 1996, 4 (05) : 173 - 173
  • [49] The pathogenesis of HIV-1 infection in the human thymus.
    Rozmyslowicz, T
    Conover, DO
    Murphy, SL
    Ratajczak, MZ
    Gaulton, GN
    [J]. BLOOD, 2000, 96 (11) : 563A - +
  • [50] ROLE OF HIV-1 BIOLOGICAL VARIABILITY IN THE PATHOGENESIS OF AIDS
    TERSMETTE, M
    SCHUITEMAKER, H
    GROENINK, M
    KOOT, M
    KEET, R
    SCHELLEKENS, PTA
    HUISMAN, JG
    MIEDEMA, F
    [J]. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1991, 4 (03): : 313 - 313
12345