Role of polymorphic variants of genes NOD2/CARD15, DLG5 and TLR4 at Crohn's disease and nonspecific ulcerative colitis

被引:0
|
作者
Malahinova, N. A. [1 ]
Shumilov, P., V [1 ]
Mukhina, J. G. [1 ]
机构
[1] Russian State Med Univ, Moscow, Russia
来源
YAKUT MEDICAL JOURNAL | 2010年 / 02期
关键词
Crohn's disease; nonspecific ulcerative colitis; gene NORD2/CARD15; gene DLG5; gene TLR4; a genetic predisposition;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The review presents data on the influence of polymorphic variants of genes NORD2/CARD15, DLG5, TLR4 on the disease progressing, age of manifestation, frequency of complications, and the length of the inflammatory process along the intestine at the inflammatory bowel disease.
引用
收藏
页码:50 / 53
页数:4
相关论文
共 50 条
  • [31] Mutations in NOD2/CARD15 in Crohn's disease patients and their unaffected siblings
    Esters, N
    Pierik, M
    Claessens, G
    Joossens, S
    Vermeire, S
    Vlietinck, R
    Rutgeerts, P
    GASTROENTEROLOGY, 2002, 122 (04) : A295 - A295
  • [32] The role of the NOD2/CARD15 gene in surgical treatment prediction in patients with Crohn's disease
    Kunovsky, L.
    Kala, Z.
    Marek, F.
    Dolina, J.
    Poredska, K.
    Kucerova, L.
    Benesova, K.
    Mitas, L.
    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2019, 34 (02) : 347 - 351
  • [33] Role of NOD2/CARD15 in coronary heart disease
    Nour Eddine El Mokhtari
    Stephan J Ott
    Almut Nebel
    Arne Schäfer
    Philip Rosenstiel
    Matti Förster
    Michael Nothnagel
    Rüdiger Simon
    Stefan Schreiber
    BMC Genetics, 8
  • [34] Sequence variation in the CARD15 (NOD2) gene and susceptibility to Crohn's disease
    Onnie, C
    King, K
    Mirza, M
    Fisher, S
    Cuthbert, A
    Hampe, J
    Mansfield, J
    Forbes, A
    Sanderson, J
    Lewis, K
    Mathew, C
    GASTROENTEROLOGY, 2003, 124 (04) : A374 - A374
  • [35] Role of CARD15/Nod2 in the regulation of the host's response to pathogens in patients with Crohn's disease
    Desreumaux, P
    GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 2002, 26 (11): : 1065 - 1066
  • [36] The P268S and M863V Polymorphisms of the NOD2/CARD15 Gene in Crohn's Disease and Ulcerative Colitis
    Diler, Songul Budak
    Polat, Fikriye
    Yaras, Serkan
    CYTOLOGY AND GENETICS, 2019, 53 (05) : 424 - 429
  • [37] Role of NOD2/CARD15 in coronary heart disease
    El Mokhtari, Nour Eddine
    Ott, Stephan J.
    Nebel, Almut
    Schafer, Arne
    Rosenstiel, Philip
    Foerster, Matti
    Nothnagel, Michael
    Simon, Ruediger
    Schreiber, Stefan
    BMC GENETICS, 2007, 8 (1)
  • [38] The P268S and M863V Polymorphisms of the NOD2/CARD15 Gene in Crohn’s Disease and Ulcerative Colitis
    Songül Budak Diler
    Fikriye Polat
    Serkan Yaraş
    Cytology and Genetics, 2019, 53 : 424 - 429
  • [39] Variants of CARD15/NOD2 associated with Crohn's disease and blau syndrome differ from wild type NOD2 in regulating cytokine secretion induced by TLR2 and TLR4 agonists in a transduced macrophage cell line
    Davey, Michael
    Zhang, Zili
    Martin, Tammy
    Rosenzweig, Holly
    Planck, Steven
    Rosenbaum, James
    CLINICAL IMMUNOLOGY, 2007, 123 : S135 - S136
  • [40] Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis
    McGovern, DPB
    van Heel, DA
    Negoro, K
    Ahmad, T
    Jewell, DP
    AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (06) : 1465 - 1466