ANTI-IDIOTYPICAL RESPONSE TO THE EXPERIMENTAL INJECTION OF INACTIVATED OR LIVE INFLUENZA-VIRUS

被引:0
|
作者
KOSITSKAYA, LS [1 ]
SOFRONOV, BN [1 ]
BICHURINA, MA [1 ]
BRYANTSEVA, EA [1 ]
ROZAEVA, NR [1 ]
FRIDMAN, EA [1 ]
机构
[1] PASTEUR EPIDEMIOL & MICROBIOL RES INST,LENINGRAD,USSR
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D O I
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中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The injection of inactivated and live influenza virus into rabbits induces the formation of anti-idiotypical antibodies, appearing after anti-influenza hemagglutinins, in the blood. The presence of immune complexes antibody - anti-idiotypical antibody in the blood of the animals has been established. The booster immunization of the animals with anfluenza virus antigens produces a rise in the levels of both idiotypical and anti-idiotypical antibodies. The injection of autologous anti-idiotypical globulin into the primed animals ensures the induction of idiotypical and anti-idiotypical revaccinal reactions.
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页码:50 / 53
页数:4
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