APPEARANCE OF RESISTANCE TO BETA-LACTAM ANTIBIOTICS DURING THERAPY FOR STREPTOCOCCUS-PNEUMONIAE MENINGITIS

被引：13

作者：

MUNOZ, M

VALDERRABANOS, ES

DIAZ, E

SILVA, JJ

SOULT, JA

INFANTE, P

LOPEZ, JD

GARCIACURIEL, A

机构：

[1] UNIV SEVILLE, VIRGEN ROCIO CHILDRENS HOSP, SCH MED, DEPT PEDIAT, SEVILLE, SPAIN

[2] UNIV SEVILLE, VIRGEN ROCIO CHILDRENS HOSP, SCH MED, DEPT MICROBIOL, SEVILLE, SPAIN

来源：

JOURNAL OF PEDIATRICS | 1995年 / 127卷 / 01期

关键词：

D O I：

10.1016/S0022-3476(95)70264-4

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A young boy had meningitis caused by Streptococcus pneumoniae that was relatively resistant to penicillin and susceptible to cefotaxime. After 10 days of therapy with penicillin and cefotaxime, fever recurred and a second lumbar puncture revealed a pneumococcus that was resistant to all beta-lactam antibiotics. We now add vancomycin to empiric third-generation cephalosporin therapy for meningitis in children when gram-positive cocci are seen on the cerebrospinal fluid smear.

引用

页码：98 / 99

页数：2

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