APPEARANCE OF RESISTANCE TO BETA-LACTAM ANTIBIOTICS DURING THERAPY FOR STREPTOCOCCUS-PNEUMONIAE MENINGITIS

被引：13
|
作者：
MUNOZ, M
VALDERRABANOS, ES
DIAZ, E
SILVA, JJ
SOULT, JA
INFANTE, P
LOPEZ, JD
GARCIACURIEL, A
机构：
[1] UNIV SEVILLE, VIRGEN ROCIO CHILDRENS HOSP, SCH MED, DEPT PEDIAT, SEVILLE, SPAIN
[2] UNIV SEVILLE, VIRGEN ROCIO CHILDRENS HOSP, SCH MED, DEPT MICROBIOL, SEVILLE, SPAIN
来源：
JOURNAL OF PEDIATRICS | 1995年 / 127卷 / 01期
关键词：
D O I：
10.1016/S0022-3476(95)70264-4
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
A young boy had meningitis caused by Streptococcus pneumoniae that was relatively resistant to penicillin and susceptible to cefotaxime. After 10 days of therapy with penicillin and cefotaxime, fever recurred and a second lumbar puncture revealed a pneumococcus that was resistant to all beta-lactam antibiotics. We now add vancomycin to empiric third-generation cephalosporin therapy for meningitis in children when gram-positive cocci are seen on the cerebrospinal fluid smear.
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页码：98 / 99
页数：2
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