Comparison of Metformin and Insulin for the Management of Gestational Diabetes

Aims: To Compare the efficacy of metformin versus insulin in term of glycaemic control for treatment of Gestational diabetes mellitus. Study design: It was a descriptive study. Duration: Six months from 1 Jan 2012 to 30 June 2012 Settings: Department of Obstetrics & Gynaecology. Results: A total of 200 cases (100 in each group) were enrolled, 61(61%) in Group-A and 55(55%) in Group-B were between 20-30 years and 39(39%) in Group-A and 45(45%) in Group-B were between 31-35 years. Mean +/- SD: was calculated as 29.43 +/- 3.51 years. Comparison of glycemic control was recorded as 72(72%)) in Group-A and 56(56%) in Group-B while remaining 28(28%) in Group-A and 44(44%) were not recorded with glycemic control. P value was calculated as 0.01 which is statistically significant. Conclusion: Metformin in term of glycaemic control for treatment of Gestational diabetes mellitus is significantly better than insulin.