DETERMINATION OF MONOFLUOROPHOSPHATE, ORTHOPHOSPHATE, AND POLYPHOSPHATES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH A PHOTODIODE ARRAY DETECTOR

Monofluorophosphate (MFP, P03F2-), rather than sodium fluoride, has been extensively used in commercial dentifrices as a fluorine donor as reported in a special issue on Monofluorophosphate Perspectives.1MFP provides a cariespreventive effect that is generally considered to involve the conversion of hydroxyapatite to more caries-resistant fluoroapatite by the action of the fluoride ion produced by the hydrolysis of MFP to orthophosphate (P1, PO43-). © 1992, American Chemical Society. All rights reserved.