EFFECT OF CHLORPROMAZINE ON THE TOXICITY OF DOXORUBICIN IN MICE

被引：0
|
作者：
SHIBATA, H
MAEKAWA, I
FURUSAWA, S
KAWAUCHI, H
TAKAYANAGI, Y
SASAKI, K
机构：
来源：
RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY | 1991年 / 71卷 / 03期
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中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
The effect of chlorpromazine (CPZ) on the toxicity of doxorubicin (DOX) were investigated in mice. CPZ significantly enhanced the acute toxicity and bone marrow toxicity induced by DOX. These results suggest the potentiation of DOX toxicity by CPZ is due to increase of sensitivity of mice to DOX.
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页码：381 / 384
页数：4
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