Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis

被引:3
|
作者
Kuo, James C. [1 ]
Hawkins, Carolyn A. [2 ,3 ]
Yip, Desmond [1 ,3 ]
机构
[1] Canberra Hosp, Dept Med Oncol, Yamba Dr, Garran, ACT 2605, Australia
[2] Canberra Hosp, Dept Immunol, Garran, ACT 2605, Australia
[3] Australian Natl Univ, ANU Med Sch, Canberra, ACT 0200, Australia
关键词
Skin Tests; Lung Diseases; Interstitial; Antineoplastic Agents; Antibodies; Monoclonal; Hypersensitivity;
D O I
10.5415/apallergy.2015.5.4.234
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to be continued and avoiding limiting treatment options for patients. We report what we believe to be the first published case of hypersensitivity skin testing for gemcitabine-induced pneumonitis in a patient with metastatic leiomyosarcoma and another case of docetaxel-induced pneumonitis in a patient with metastatic HER2-positive breast cancer.
引用
收藏
页码:234 / 236
页数:3
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