Particular aspects of arythmogene myocardial ischemia in patients with stable pectoral angina

Objectives. The aim of study was to determine the relations between myocardic transitory ischemia, ventricular potential malign arrhythmia and angiocoronarographic, echographic, electrocardiographic data in patients (pts) with stabile coronary artery disease. Methods. 765 patients with stabile angina and ventricular potential malign arrhythmia were evaluated angiocoronarographic, echographic, standard ECG, Holter ECG, radiologic, and stress test. Results. Anomalies of wall motion preferential located on the anterior wall and number segments with contractility anomalies are independent risk factors for AVPM appearance. Arhytmogenic pattern of stabile CAD appeared at: 3 - vessel disease, LAD stenosis >= 75% and >= 95%, representing independent risk factors for AVPM appearance. Conclusions. Arhytmogenic pattern of stabile CAD is caracterisated by: tri-coronariane extensive lesions >= 75% preferential located LM and proximal LAD, multiple wall motion anomalies dominant localisated at anterior wall, prior myocardial infarction, low LVEF, important, prolonged ischemic episodes with increase of interval QTc > 450 ms.