WOBBLE POSITION MODIFIED NUCLEOSIDES EVOLVED TO SELECT TRANSFER-RNA CODON RECOGNITION - A MODIFIED-WOBBLE HYPOTHESIS

被引：91
|
作者：
AGRIS, PF
机构：
[1] Department of Biochemistry, North Carolina State University, Raleigh, NC 27695-7622
来源：
BIOCHIMIE | 1991年 / 73卷 / 11期
基金：
美国国家科学基金会;
关键词：
WOBBLE NUCLEOSIDE; MODIFIED-WOBBLE HYPOTHESIS; THIO-URIDINE; MODIFIED NUCLEOSIDES;
D O I：
10.1016/0300-9084(91)90163-U
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
While recognized that some wobble exists in the base pairing of the first base of the tRNA anticodon with the third of the codon, specific base modifications have evolved to select particular codons. This modified-wobble theory would be exemplified by a single codon recognition imposed on the anticodon by modification of the tRNA wobble position nucleoside.
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页码：1345 / 1349
页数：5
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