LANGERHANS CELL HISTIOCYTOSIS IN CHILDHOOD - MANAGEMENT OF HEAD AND NECK MANIFESTATIONS

被引:0
|
作者
IRVING, RM
BROADBENT, V
JONES, NS
机构
[1] ADDENBROOKES HOSP,DEPT PAEDIAT ONCOL,CAMBRIDGE CB2 2QQ,ENGLAND
[2] HOSP SICK CHILDREN,DEPT PAEDIAT OTOLARYNGOL,LONDON,ENGLAND
来源
LARYNGOSCOPE | 1994年 / 104卷 / 01期
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The authors carried out a retrospective analysis of 131 cases of Langerhans' cell histiocytosis treated at two centers over a 30 year period. Ah those with head and neck manifestations have been reviewed with particular reference to management and outcome. The role of chemotherapy, radiotherapy, and surgery is discussed, and we present our results of the successful introduction of topical nitrogen mustard (Mustine((R))) ear drops for meatal skin involvement. During the period of the study our modus operandi has evolved from an aggressive medical and surgical approach, favored early in the series, to our present more conservative approach, with an attendant reduction in morbidity.
引用
收藏
页码:64 / 70
页数:7
相关论文
共 50 条
  • [41] Oral Manifestations May Be the First Sign of Langerhans Cell Histiocytosis
    Erdem, Arzu Pinar
    Kasimoglu, Yelda
    Sepet, Elif
    Gencay, Koray
    Sahin, Songul
    Dervisoglu, Sergulen
    ORAL HEALTH & PREVENTIVE DENTISTRY, 2013, 11 (01) : 57 - 59
  • [42] INTRACRANIAL MANIFESTATIONS OF LANGERHANS CELL HISTIOCYTOSIS - MR-IMAGING
    KUJAT, C
    HERMES, M
    HEIDE, G
    BAUMLER, S
    FEIDEN, W
    RADIOLOGE, 1994, 34 (11): : 648 - 655
  • [43] Oral manifestations of Langerhans' cell histiocytosis: Review and report of case
    Shirley, JC
    Thornton, JB
    JOURNAL OF DENTISTRY FOR CHILDREN, 2000, 67 (04) : 293 - 296
  • [44] Oral manifestations of Langerhans cell histiocytosis with unusual histomorphologic features
    AbdullGaffar, Badr
    Awadhi, Farzad
    ANNALS OF DIAGNOSTIC PATHOLOGY, 2020, 47
  • [45] An enigmatic disease: childhood Langerhans cell histiocytosis in 2005
    Savasan, S
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 2006, 45 (03) : 182 - 188
  • [46] Permanent disabilities in childhood survivors of Langerhans cell histiocytosis
    Kusumakumary, P
    James, FV
    PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2000, 17 (05) : 375 - 381
  • [47] Cutaneous variants of Langerhans cell histiocytosis in early childhood
    Gille, J
    Spieth, K
    Kaufmann, R
    HAUTARZT, 2000, 51 (12): : 939 - 944
  • [48] Clinical presentation and epidemiology of childhood Langerhans cell Histiocytosis
    Donadieu, J.
    Guyot-Goubin, A.
    Clavel, J.
    Thomas, C.
    ARCHIVES DE PEDIATRIE, 2008, 15 (05): : 520 - 522
  • [49] A Rare Cause of Proptosis in Childhood: Langerhans Cell Histiocytosis
    Vatansever, Mustafa
    Vatansever, Esra
    Dinc, Erdem
    Sari, Ayca
    Kara, Tuba
    TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY, 2016, 46 (04): : 194 - 196
  • [50] Childhood Langerhans cell histiocytosis: a disease with many faces
    Alexander K. C. Leung
    Joseph M. Lam
    Kin Fon Leong
    World Journal of Pediatrics, 2019, 15 : 536 - 545