STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED TETRAHYDROFURANS - IDENTIFICATION AND ANALYSIS BY PROTON NMR AND MNDO, MM2 CALCULATIONS

被引：14

作者：

TARAKESHWAR, P ^{[1
]}

IQBAL, J ^{[1
]}

MANOGARAN, S ^{[1
]}

机构：

[1] INDIAN INST TECHNOL,DEPT CHEM,KANPUR 208016,UTTAR PRADESH,INDIA

来源：

TETRAHEDRON | 1991年 / 47卷 / 02期

关键词：

D O I：

10.1016/S0040-4020(01)80924-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl acetoacetate and terminal olefins react in the presence of cobalt(II) acetate and oxygen to give 5-alkyl-2-hydroxy-2-methyl-3-methoxycarbonyl tetrahydrofurans in a highly stereoselective manner. Proton NMR, semiempirical MNDO and empirical MM2 methods are used to identify the particular diastereomer and the energetics of the different isomers are discussed.

引用

页码：297 / 304

页数：8

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