user

MURINE HYBRIDOMAS SECRETING MONOCLONAL-ANTIBODIES REACTING WITH MLS(A) ANTIGENS

被引：0
|
作者：
DEGIORGI, L [1 ]
DEMATOS, C [1 ]
ELLIS, BA [1 ]
MATOSSIANROGERS, A [1 ]
机构：
[1] ROYAL LONDON HOSP,COLL MED,DEPT IMMUNOL,LONDON,ENGLAND
来源：
EXPERIMENTAL AND CLINICAL IMMUNOGENETICS | 1993年 / 10卷 / 04期
关键词：
ANTI-SELF-ANTIBODY; MONOCLONAL ANTIIDIOTYPIC ANTIBODY; ANTI-MLS(A) ANTIBODY;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Murine monoclonal antibodies have been developed from spleens of AKR mice hyperimmunised with the monoclonal antibody against TCR-Vbeta6. Two new monoclonal antibodies called AL-12-3 and AL-32-7 were able to specifically block Mls(a)-induced but not MHC-induced mixed lymphocyte responses in a dose-dependent manner. Both antibodies are mouse IgG3 lambda chain isotype and bind to Mls(a)-bearing lymphocytes from different strains of mice. The availability of such antibodies may well facilitate future research aimed at immunochemical and molecular characterization of Mls de terminants.
引用
收藏
页码：219 / 223
页数：5
相关论文
共 50 条
  • [31] CHARACTERIZATION OF HUMAN-SPERM ANTIGENS BY MURINE MONOCLONAL-ANTIBODIES
    BARNIER, R
    PEREZ, E
    [J]. ARCHIVOS DE BIOLOGIA Y MEDICINA EXPERIMENTALES, 1986, 19 (02): : R177 - R177
  • [32] USE OF MONOCLONAL-ANTIBODIES FOR ISOLATION AND CHARACTERIZATION OF MURINE HISTOCOMPATIBILITY ANTIGENS
    YUROVSKY, VV
    VASILOV, RG
    [J]. BIOLOGICHESKIE MEMBRANY, 1984, 1 (08): : 814 - 822
  • [33] PREPARATION AND CHARACTERIZATION OF HYBRIDOMAS SECRETING MONOCLONAL-ANTIBODIES TO TICK-BORNE ENCEPHALITIS-VIRUS
    KUSHCH, AA
    NOVAK, M
    MELNIKOVA, YE
    GAIDAMOVICH, SY
    GRESIKOVA, M
    SEKEYOVA, M
    NOVOKHATSKY, AS
    MIKHEEVA, TG
    SVESHNIKOVA, NA
    BORECKY, L
    ZHDANOV, VM
    [J]. ACTA VIROLOGICA, 1986, 30 (03) : 199 - 205
  • [34] PREPARATION AND CHARACTERIZATION OF MURINE MONOCLONAL-ANTIBODIES TO SWINE LYMPHOCYTE ANTIGENS
    LIE, WR
    ROTHSCHILD, MF
    WARNER, CM
    [J]. IMMUNOLOGY, 1988, 64 (04) : 599 - 605
  • [35] EFFECTIVE PRODUCTION BY ELECTROFUSION OF HYBRIDOMAS SECRETING MONOCLONAL-ANTIBODIES AGAINST HC-ANTIGEN OF SALMONELLA
    TSONEVA, I
    TOMOV, T
    PANOVA, I
    STRAHILOV, D
    [J]. BIOELECTROCHEMISTRY AND BIOENERGETICS, 1990, 24 (01): : 41 - 49
  • [36] GENERATION AND CHARACTERIZATION OF HAMSTER-MOUSE HYBRIDOMAS SECRETING MONOCLONAL-ANTIBODIES WITH SPECIFICITY FOR LIPOPOLYSACCHARIDE RECEPTOR
    BRIGHT, SW
    CHEN, TY
    FLEBBE, LM
    LEI, MG
    MORRISON, DC
    [J]. JOURNAL OF IMMUNOLOGY, 1990, 145 (01): : 1 - 7
  • [37] DEVELOPMENT OF HYBRIDOMAS SECRETING MONOCLONAL-ANTIBODIES AGAINST HEMORRHAGIC FACTORS IN CROTALUS-ATROX VENOM
    HUANG, S
    PEREZ, JC
    [J]. TOXICON, 1985, 23 (01) : 30 - 30
  • [38] KARYOTYPE ANALYSIS OF HYBRIDOMAS PRODUCING MONOCLONAL-ANTIBODIES AGAINST DIFFERENT ANTIGENS (CELL HYBRIDS)
    KONTSEK, P
    NOVAK, M
    KONTSEKOVA, E
    [J]. FOLIA BIOLOGICA, 1988, 34 (02) : 99 - 104
  • [39] HYBRIDOMAS SYNTHESIZING MONOCLONAL-ANTIBODIES AGAINST HUMAN-LYMPHOCYTE SURFACE-ANTIGENS
    SEREGINA, TM
    MEKSHENKOV, MI
    [J]. TSITOLOGIYA, 1986, 28 (09): : 976 - 980
  • [40] ESTABLISHMENT AND CHARACTERIZATION OF PERMANENT MURINE HYBRIDOMAS SECRETING MONOCLONAL ANTI-THY-1 ANTIBODIES
    DRABER, P
    ZIKAN, J
    VOJTISKOVA, M
    [J]. JOURNAL OF IMMUNOGENETICS, 1980, 7 (06): : 455 - 474
12345