ORIGINS OF SIMIAN IMMUNODEFICIENCY VIRUS-INFECTION IN MACAQUES AT THE NEW-ENGLAND-REGIONAL-PRIMATE-RESEARCH-CENTER

被引：56

作者：

MANSFIELD, KG

LERCHE, NW

GARDNER, MB

LACKNER, AA

机构：

[1] UNIV CALIF DAVIS, SCH MED, CALIF REG PRIMATE RES CTR, DAVIS, CA 95616 USA

[2] UNIV CALIF DAVIS, SCH MED, DEPT PATHOL, DAVIS, CA 95616 USA

来源：

JOURNAL OF MEDICAL PRIMATOLOGY | 1995年 / 24卷 / 03期

关键词：

MYCOBACTERIUM AVIUM COMPLEX; LYMPHOMA; POLYMERASE CHAIN REACTION; IN SITU HYBRIDIZATION; MACACA MULATTA; CEROCEBUS ATYS;

D O I：

10.1111/j.1600-0684.1995.tb00156.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

A cohort of rhesus macaques (Macaca mulatta), obtained from the California Regional Primate Research Center (CRPRC) and necropsied in 1970-72 with lesions suggestive of simian immunodeficiency virus (SIV) infection, was identified at the New England Regional Primate Research Center (NERPRC). Polymerase chain reaction (PCR) DNA sequence analysis, and in situ hybridization were used to confirm the presence of SIV nucleic acids. This represents the earliest case of SIV infection at the NERPRC and suggests a common source for present day SIV isolates.

引用

页码：116 / 122

页数：7

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