MECHANISMS OF DEVELOPMENT OF ISCHEMIA IN THE GASTRIC MUCOSA AND ITS ROLE IN PATHOGENESIS OF STRESS-INDUCED GASTRIC ULCERS

被引：0
|
作者：
Tarasenko, L. [1 ]
Omelchenko, O. [1 ]
机构：
[1] Ukrainian Acad Med Dent, Poltava, Ukraine
来源：
WORLD OF MEDICINE AND BIOLOGY | 2010年 / 25卷 / 02期
关键词：
acute stress; free radical oxidation;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
It was found in experiments in Wistar rats that an initiating role in mechanisms of development of stress-induced gastric ulcers belongs to hemocirculatory infringements due to endothelial disfunctions and activation of synthesis of endothelin-1, that decrease the protective function and cause destructive alteration of the gastric mucosa. The severity of stress-induced gastric damage depends on the reaction type of the organism. Manifestations of the pathological changes in gastric tissues were more pronounced in stress predisposed rats as compared to stress resistant rats.
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页码：176 / 180
页数：5
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