STRUCTURE OF N,N'-DIMETHYL-4,4'-BIPYRIDYLIUM DICHLORIDE DIHYDRATE

被引：31
|
作者：
COUSSON, A
BACHET, B
KOKEL, B
HUBERTHABART, M
机构：
[1] UNIV PARIS 06,MINERAL & CRISTALLOG LAB,CNRS,LA 09,F-75230 PARIS 05,FRANCE
[2] INST CURIE,CHERCHEURS,INSERM,F-75231 PARIS 05,FRANCE
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1993年 / 49卷
关键词：
D O I：
10.1107/S0108270191015019
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
C12H14N22+.2Cl-.2H2O, M(r) = 293, triclinic, P1BAR, a = 9.696 (3), b = 11.322 (4), c = 7.076 (3) angstrom, alpha = 100.68 (4), beta = 93.40 (3), gamma = 107.04 (4)degrees, V = 724 (6) angstrom3, Z = 2, D(x) = 1.344 Mg m-3, lambda(Cu Kalpha) = 1.5418 angstrom, mu = 4.4 mm-1, F(000) = 308, room temperature, R = 0.052 for 2201 independent reflections. N,N'-dimethyl-4,4'-bipyridylium dichloride (or paraquat, viologen) like mitoguazone (an anticancer drug), affects the polyamine uptake systems, a potential target in cancer chemotherapy. The description of the three-dimensional structure of this ion should allow a better assessment of the structure-activity relationship of these bioactive molecules.
引用
收藏
页码：942 / 943
页数：2
相关论文
共 50 条
  • [31] AN ENDOR AND ELECTRON-SPIN-RESONANCE STUDY OF THE RADICAL CATION OF N,N'-BIS-(4-FLUOROPHENYL)-4,4'-BIPYRIDYLIUM DICHLORIDE
    EVANS, JC
    SORKHABI, MHN
    ROWLANDS, CC
    TETRAHEDRON, 1982, 38 (16) : 2581 - 2584
  • [32] SOME THERMODYNAMIC PROPERTIES OF AQUEOUS PARAQUAT (1,1'-DIMETHYL-4,4'-BIPYRIDYLIUM DICHLORIDE) AND ITS AQUEOUS MIXTURES WITH SODIUM CHLORIDE AT 25 DEGREES C
    PLATFORD, RF
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1970, 4 (05) : 410 - &
  • [33] Preparation, crystal structure and luminescence of lanthanide coordination polymers with 2,2′-dimethyl-4,4′-bipyridine-N,N′-dioxide
    Xu, Jing
    Chen, Min-Dong
    JOURNAL OF COORDINATION CHEMISTRY, 2013, 66 (03) : 509 - 519
  • [34] SOME PHARMACOLOGICAL STUDIES ON PARAQUAT (1,1'-DIMETHYL-4,4'-BIPYRIDINIUM DICHLORIDE)
    VERMA, SP
    BAHGA, HS
    INDIAN VETERINARY JOURNAL, 1978, 55 (05): : 385 - 389
  • [35] (2,2'-Dimethyl-4,4'-bi-1,3-thiazole-κ2 N,N')diiodidomercury(II)
    Abedi, Anita
    Bali, Effat Yahyazade
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : M1023 - U1487
  • [36] THE EFFECTS OF 24-PERCENT PARAQUAT (1,1'-DIMETHYL-4,4'-BIPYRIDYLIUM DICHLORIDE) ON HEMODYNAMICS, BLOOD-GASES, PLASMA LACTATE AND PLASMA-CATECHOLAMINES IN DOGS
    SONE, T
    TALBOT, A
    HARADA, T
    IKUO, T
    KATO, T
    UEMATSU, H
    VETERINARY AND HUMAN TOXICOLOGY, 1989, 31 (02) : 149 - 153
  • [37] N-METHYLATION AS A TOXICATION ROUTE FOR XENOBIOTICS .2. INVIVO FORMATION OF N,N'-DIMETHYL-4,4'-BIPYRIDYL ION (PARAQUAT) FROM 4,4'-BIPYRIDYL IN THE GUINEA-PIG
    GODIN, CS
    CROOKS, PA
    DRUG METABOLISM AND DISPOSITION, 1989, 17 (02) : 180 - 185
  • [38] Photoinduced electron transfer in π-donor-capped Zn(II) porphyrins and N,N′-dimethyl-4,4′-bipyridinium supramolecular assemblies
    Kaganer, E
    Joselevich, E
    Willner, I
    Chen, ZP
    Gunter, MJ
    Gayness, TP
    Johnson, MR
    JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (07): : 1159 - 1165
  • [39] 4,4′-bipyridylium bis(hydrogen 2,2′-dithiodibenzoate) dihydrate
    Hu, RF
    Wen, YH
    Zhang, J
    Li, ZJ
    Yao, YG
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2004, 60 : O2029 - O2031
  • [40] 2,2′-Dimethyl-4,4′-bipyridine
    Ibragimov, Bahtier
    Weber, Edwin
    Peukert, Max
    Fischer, Conrad
    Seichter, Wilhelm
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1287 - U2129
12345