CHANGES OF SYSTEMIC FIBRINOLYTIC AND HEMOSTATIC PARAMETERS DURING LOCAL FIBRINOLYSIS WITH TISSUE-PLASMINOGEN ACTIVATOR (RT-PA)

被引:0
|
作者
KLEIN, P
ROTH, FJ
RIEGER, H
POPOVCENIC, S
机构
[1] UNIV BONN,AGGERTALKLIN ENGELSKIRCHEN,W-5300 BONN,GERMANY
[2] UNIV BONN,INST EXPTL HAMATOL,W-5300 BONN,GERMANY
来源
VASA-JOURNAL OF VASCULAR DISEASES | 1992年 / 21卷 / 03期
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中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
During the local fibrinolysis with rt-PA (2.5 mg/h) systemic plasminogen and alpha 2-antiplasmin activities slightly decrease, but the fibrinolytic system is compensated during the whole treatment. The d-dimer plasma levels increase dependently on the mass of thrombus. Despite the administration of high doses of heparin during the fibrinolysis thrombin is formed, measured as thrombin-antithrombin III complex (TAT).
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页码:249 / 252
页数:4
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