SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING 4-O-ETHYLTHYMIDINE

被引：1

作者：

PEDROSO, E

FERNANDEZ, D

PALOM, Y

ERITJA, R

机构：

[1] Department of Organic Chemistry, University of Barcelona, E-08028 Barcelona

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期

关键词：

D O I：

10.1080/07328319108046551

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Use of p-nitrophenylethyl base protecting groups together with phosphite-triester solid-phase methodology allows the rapid and efficient preparation of oligonucleotides bearing the mutagenic base 4-O-ethylthymine, while standard base protecting groups are not compatible with the presence of this base.

引用

页码：623 / 624

页数：2

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