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- [21] Discovery of N-[(4R)-6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a Novel Cannabinoid-1 Receptor (CB1R) Inverse Agonist for the Treatment of ObesityJOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (10) : 4028 - 4037Yan, LinHuo, PeiDebenham, John S.Madsen-Duggan, Christina B.Lao, JulieChen, Richard Z.Xiao, Jing ChenShen, Chun-PynStribling, D. SloanShearman, Lauren P.Strack, Alison M.Tsou, NancyBall, Richard G.Wang, JunyingTong, XinchunBateman, Thomas J.Reddy, Vijay B. G.Fong, Tung M.Hale, Jeffrey J.
- [22] CHIRAL SYNTHESIS OF 6,7-BENZOMORPHANS - SYNTHESIS OF (-)1(S),2(S),4(R),6(R)-1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-8-METHOXY-1,3,4,6-TETRAMETHYL-3-BENZAZOCINE THROUGH THE CHROMIUM HEXACARBONYL MEDIATED CYCLIZATION OF 1(S),1'(R)-1,2-DIHYDRO-7-METHOXY-1,4-DIMETHYL-1-(N-METHYL-N-TRIFLUOROACETAMIDO-1'-METHYLETHAN-2'-YL)NAPHTHALENETETRAHEDRON, 1991, 47 (24) : 4195 - 4210SAINSBURY, MMAHON, MFWILLIAMS, CSNAYLOR, ASCOPES, DIC
- [23] Characterization of (2S,4R)-1-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a selective and orally active vasopressin V1b receptor antagonistJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 300 (03): : 1122 - 1130Serradeil-Le Gal, CWagnon, JSimiand, JGriebel, GLacour, CGuillon, GBarberis, CBrossard, GSoubrié, PNisato, DPascal, MPruss, RScatton, BMaffrand, JPLe Fur, G