CISAPRIDE IN CHRONIC DYSPEPSIA - RESULTS OF A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

被引:24
|
作者
CHUNG, JM
机构
[1] Dept. of Internal Medicine, School of Medicine, Kyungbook National University, Taegu
关键词
CHRONIC DYSPEPSIA; CISAPRIDE;
D O I
10.3109/00365529309098323
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The efficacy and tolerability of cisapride in chronic dyspepsia was evaluated in a randomized, double-blind, placebo-controlled study. After 4 weeks' treatment with oral cisapride 10 mg three times daily (n = 14), bloating and epigastric discomfort were significantly reduced compared with placebo (n = 15; p < 0.05). Moreover, the global response to treatment was excellent or good in 71.4% of patients in the cisapride group versus 20.0% with placebo. No significant side effects were observed. It is concluded that cisapride is an effective and well-tolerated treatment for chronic dyspepsia.
引用
收藏
页码:11 / 14
页数:4
相关论文
共 50 条
  • [31] OXATOMIDE IN THE TREATMENT OF CHRONIC URTICARIA - A DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL
    PEREMANS, W
    MERTENS, RLJ
    MORIAS, J
    CAMPAERT, H
    DERMATOLOGICA, 1981, 162 (01): : 42 - 50
  • [32] Cisapride in the control of symptoms in infants with gastroesophageal reflux: A randomized, double-blind, placebo-controlled trial
    Cohen, RC
    O'Loughlin, EV
    Davidson, GP
    Moore, DJ
    Lawrence, DM
    JOURNAL OF PEDIATRICS, 1999, 134 (03): : 287 - 292
  • [33] Response to topiramate in the prevention of chronic migraine: results of a double-blind, randomized, placebo-controlled trial
    Grazzi, L.
    Diener, H-C
    Van Oene, J. C.
    Lahaye, M.
    Schwalen, S.
    Goadsby, P. J.
    CEPHALALGIA, 2006, 26 (11) : 1368 - 1368
  • [34] CLONAZEPAM TREATMENT OF CHRONIC-SCHIZOPHRENIA - NEGATIVE RESULTS IN A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
    KARSON, CN
    WEINBERGER, DR
    BIGELOW, L
    WYATT, RJ
    AMERICAN JOURNAL OF PSYCHIATRY, 1982, 139 (12): : 1627 - 1628
  • [35] Treatment of functional dyspepsia with a herbal preparation - A double-blind, randomized, placebo-controlled, multicenter trial
    Madisch, A
    Holtmann, G
    Mayr, G
    Vinson, B
    Hotz, J
    DIGESTION, 2004, 69 (01) : 45 - 52
  • [36] Efficacy and Safety of Nortriptyline in Functional Dyspepsia in Asians: A Randomized Double-Blind Placebo-Controlled Trial
    Kaosombatwattana, Uayporn
    Pongprasobchai, Supot
    Limsrivilai, Julajak
    Leelakusolvong, Somchai
    Tanwandee, Tawesak
    GASTROENTEROLOGY, 2015, 148 (04) : S822 - S822
  • [37] Effect of profound acid suppression in functional dyspepsia:: a double-blind, randomized, placebo-controlled trial
    Bolling-Sternevald, E
    Lauritsen, K
    Aalykke, C
    Havelund, T
    Knudsen, T
    Unge, P
    Ekström, P
    Jaup, B
    Norrby, A
    Stubberöd, A
    Melén, K
    Carlsson, R
    Jerndal, P
    Junghard, O
    Glise, H
    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2002, 37 (12) : 1395 - 1402
  • [38] Efficacy and safety of nortriptyline in functional dyspepsia in Asians: A randomized double-blind placebo-controlled trial
    Kaosombatwattana, Uayporn
    Pongprasobchai, Supot
    Limsrivilai, Julajak
    Maneerattanaporn, Monthira
    Leelakusolvong, Somchai
    Tanwandee, Tawesak
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2018, 33 (02) : 411 - 417
  • [39] DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF KETAZOLAM IN ANXIETY
    BOWDEN, CL
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1978, 24 (02): : 170 - 178
  • [40] BROMOCRIPTINE IN MANIA - PLACEBO-CONTROLLED DOUBLE-BLIND TRIAL
    SMITH, AHW
    CHAMBERS, C
    NAYLOR, GJ
    BRITISH MEDICAL JOURNAL, 1980, 280 (6207): : 86 - 86