ULTRASTRUCTURE OF MESOTHELIAL REGENERATION AFTER INTRAPERITONEAL INJECTION OF ASBESTOS FIBERS ON RAT OMENTUM

被引：1
|
作者：
GONZALEZ, S
FRIEMANN, J
MULLER, KM
POTT, F
机构：
[1] RUHR UNIV BOCHUM,KLIN,INST PATHOL BERUFSGENOSSENSCH KRANKENANSTALTEN BERGMANNSHEIL,W-4630 BOCHUM,GERMANY
[2] UNIV DUSSELDORF,MED INST UMWELTHYG,W-4000 DUSSELDORF 1,GERMANY
来源：
PATHOLOGY RESEARCH AND PRACTICE | 1991年 / 187卷 / 08期
关键词：
MESOTHELIUM; ASBESTOS; MESOTHELIOMA; CARCINOGENESIS; MYOFIBROBLASTS;
D O I：
10.1016/S0344-0338(11)81062-9
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
In order to describe the ultrastructural features of the early phases of regenerating mesothelium in rat peritoneum, 69 cases were examined after intraperitoneal injection of 0.05-15 mg crocidolite, chrysotile B and other mineral and synthetic fibers. The findings show the presence of intermediate or transition cells between proliferating submesothelial connective tissue cells bearing the ultrastructural phenotype of myofibroblasts and mature fully regenerated mesothelium. Our results and data accumulated in the literature provide strong support for the hypothesis of submesothelial cell origin for regenerating mesothelium.
引用
收藏
页码：931 / 935
页数：5
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