THE TOTAL SYNTHESIS OF PACLITAXEL BY ASSEMBLY OF THE RING-SYSTEM

被引:0
|
作者
NICOLAOU, KC [1 ]
GUY, RK [1 ]
机构
[1] UNIV CALIF SAN DIEGO, DEPT CHEM, LA JOLLA, CA 92037 USA
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D O I
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Taxol is an important anticancer agent that is active in a number of cancers including breast and ovarian. The total synthesis of Taxol has been a goal for numerous synthetic groups over the past two decades. Presented herein is the total synthesis of the natural enantiomer of Taxol.
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页码:302 / 312
页数:11
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