PRENATAL-DIAGNOSIS OF HETEROZYGOUS DEFICIENCY OF THE 2ND COMPONENT OF COMPLEMENT

被引：2
|
作者：
SULLIVAN, KE [1 ]
WINKELSTEIN, JA [1 ]
机构：
[1] JOHNS HOPKINS UNIV,SCH MED,DEPT PEDIAT,DIV ALLERGY & IMMUNOL,BALTIMORE,MD 21205
来源：
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 1994年 / 1卷 / 05期
关键词：
D O I：
10.1128/CDLI.1.5.606-607.1994
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Genetically determined C2 deficiency predisposes an individual to recurrent and invasive bacterial infections as well as a variety of rheumatic diseases. Most C2-deficient individuals carry the same 28-bp deletion in the sixth exon of the C2 gene. The present article reports the first prenatal analysis of a sibling of a C2-deficient patient; the sibling was found to be a heterozygous carrier of the 28-bp deletion of C2.
引用
收藏
页码：606 / 607
页数：2
相关论文
共 50 条
12345