BASE-LINE AND EARLY NATURAL-HISTORY REPORT - THE CENTRAL VEIN OCCLUSION STUDY

被引:0
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作者
CLARKSON, JG [1 ]
CHUANG, E [1 ]
GASS, D [1 ]
PEDROSO, M [1 ]
CUBILLAS, T [1 ]
DURIA, ES [1 ]
HESS, DJ [1 ]
RAMS, I [1 ]
BALL, M [1 ]
GUTIERREZ, A [1 ]
KIES, P [1 ]
MUNIZ, N [1 ]
PALL, M [1 ]
PAPPAS, C [1 ]
FINKELSTEIN, D [1 ]
PATZ, A [1 ]
RYTEL, D [1 ]
BELT, J [1 ]
CAIN, D [1 ]
CAIN, T [1 ]
EMMERT, D [1 ]
GEORGE, T [1 ]
HERRING, M [1 ]
SOTIRAKOS, P [1 ]
ORTH, DH [1 ]
FLOOD, TP [1 ]
LARSEN, T [1 ]
PEREZ, N [1 ]
BRYANT, D [1 ]
DOHERTY, D [1 ]
FITZGERALD, J [1 ]
GORDON, M [1 ]
HOLOD, C [1 ]
KWIATKOWSKI, K [1 ]
MACLEOD, C [1 ]
MORRISON, C [1 ]
WESTCOTT, C [1 ]
KLEIN, ML [1 ]
WILSON, D [1 ]
WELEBER, RG [1 ]
NOLTE, S [1 ]
HURLBURT, N [1 ]
EVANS, M [1 ]
WALLACE, P [1 ]
STEINKAMP, P [1 ]
FUNKNER, D [1 ]
GORDON, C [1 ]
TREMPE, C [1 ]
JALKH, A [1 ]
WEITER, J [1 ]
机构
[1] TEXAS A&M UNIV SYST,HLTH SCI CTR,CTR CENT VEIN OCCLUS STUDY COORDINATING,2401 S 31ST ST,TEMPLE,TX 76508
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中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Objectives: To evaluate panretinal photocoagulation for ischemic central vein occlusion and macular grid-pattern photocoagulation for macular edema with reduced visual acuity due to central vein occlusion and to further define the natural history of central vein occlusion. Design: A multicenter randomized controlled clinical trial supported by the National Eye Institute, Bethesda, Md. Patients: A total of 728 eyes from 725 patients were entered into one or more of four study groups: perfused, nonperfused, indeterminate perfusion, and macular edema. Results: Follow-up of study patients is still in progress and no results are available for the randomized groups (nonperfused and macular edema). Thirty-eight (83%) of 46 evaluable eyes in the indeterminate group eventually demonstrated at least 10 disc areas of nonperfusion (28 eyes) or developed iris and/or angle neovascularization before retinal status could be determined (10 eyes). Four-month follow-up information is available for 522 of the 547 eyes in the perfused group. Thirty of these 522 eyes demonstrated iris and/or angle neovascularization at or before the 4-month follow-up visit. An additional 51 eyes had developed evidence of at least 10 disc areas of nonperfusion by the time of the 4-month visit. Conclusions: These findings confirm the importance of frequent follow-up examinations, including undilated slit-lamp examination of the iris, and gonioscopy in the management of all patients with recent onset of central vein occlusion.
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页码:1087 / 1095
页数:9
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