PROGUANIL - THE ISOLATION OF A METABOLITE WITH HIGH ANTIMALARIAL ACTIVITY

被引:72
|
作者
CROWTHER, AF
LEVI, AA
机构
来源
关键词
D O I
10.1111/j.1476-5381.1953.tb00758.x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:93 / 97
页数:5
相关论文
共 50 条
  • [41] THE ISOLATION OF A METABOLITE OF PENTOBARBITAL
    MAYNERT, EW
    VANDYKE, HB
    SCIENCE, 1949, 110 (2868) : 661 - 662
  • [42] Antimalarial diterpenoids from Vitex rotundifolia : Isolation, structure elucidation, and in vitro antiplasmodial activity
    Kim, You Ah
    Latif, Abdul
    Kong, Chang-Suk
    Seo, Youngwan
    Dalal, Seema R.
    Cassera, Maria B.
    Kingston, David G., I
    BIOORGANIC CHEMISTRY, 2020, 100
  • [43] Bullous erythema multiforme after treatment with Malarone®, a combination antimalarial composed of atovaquone and proguanil hydrochloride
    Remich, Shon A.
    Polhemus, Mark E.
    Ogutu, Bernhards
    Walsh, Douglas S.
    TROPICAL DOCTOR, 2008, 38 (03) : 190 - 191
  • [44] Evaluation of ethnopharmacologically selected Vitex negundo L. for In vitro antimalarial activity and secondary metabolite profiling
    Dwivedi, Manish Kumar
    Shukla, Ravindra
    Sharma, Naveen Kumar
    Manhas, Ashan
    Srivastava, Kumkum
    Kumar, Niti
    Singh, Prashant Kumar
    JOURNAL OF ETHNOPHARMACOLOGY, 2021, 275
  • [45] PEROXIDATION OF THE ANTIMALARIAL DRUG PRIMAQUINE - CHARACTERIZATION OF A BENZIDINE-LIKE METABOLITE WITH METHEMOGLOBIN-FORMING ACTIVITY
    MORAIS, MD
    AUGUSTO, O
    XENOBIOTICA, 1993, 23 (02) : 133 - 139
  • [46] Formation of the diuretic chlorazanil from the antimalarial drug proguanil-Implications for sports drug testing
    Thevis, Mario
    Geyer, Hans
    Thomas, Andreas
    Tretzel, Laura
    Bailloux, Isabelle
    Buisson, Corinne
    Lasne, Francoise
    Schaefer, Maximilian S.
    Kienbaum, Peter
    Mueller-Stoever, Irmela
    Schaenzer, Wilhelm
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2015, 115 : 208 - 213
  • [47] AN ALKALOID WITH HIGH ANTIMALARIAL ACTIVITY FROM DICHROA-FEBRIFUGA
    KOEPFLI, JB
    MEAD, JF
    BROCKMAN, JA
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1947, 69 (07) : 1837 - 1837
  • [48] Polyaniline-cobalt oxide nanofibers for simultaneous electrochemical determination of antimalarial drugs: Primaquine and proguanil
    Nate, Zondi
    Gill, Atal A. S.
    Chauhan, Ruchika
    Karpoormath, Rajshekhar
    MICROCHEMICAL JOURNAL, 2021, 160
  • [49] THE ACTIVATION OF THE BIGUANIDE ANTIMALARIAL PROGUANIL CO-SEGREGATES WITH THE MEPHENYTOIN OXIDATION POLYMORPHISM - A PANEL STUDY
    WARD, SA
    HELSBY, NA
    SKJELBO, E
    BROSEN, K
    GRAM, LF
    BRECKENRIDGE, AM
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1991, 31 (06) : 689 - 692
  • [50] Pharmacokinetic evaluation and metabolite characterization of the antimalarial piperaquine in the rat
    Tarning, J.
    Lindegardh, N.
    Sandberg, S.
    Day, N.
    White, N.
    Ashton, M.
    TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2007, 12 : 224 - 224