THE CD19/CD21 SIGNAL-TRANSDUCTION COMPLEX OF B-LYMPHOCYTES

被引:227
|
作者
TEDDER, TE
ZHOU, LJ
ENGEL, P
机构
[1] Thomas F. Tedder, Liang-Ji Zhou and Pablo Engel are at the Detp of Immunology, Duke University Medical Center, Durham, NC 27710
来源
IMMUNOLOGY TODAY | 1994年 / 15卷 / 09期
关键词
D O I
10.1016/0167-5699(94)90274-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
CD19 and CD21 are B-cell surface molecules that associate with each other and with CD81 and Leu-13 to generate a signal transduction complex that is independent of the antigen receptor. Current studies, reviewed here by Thomas Tedder, Liang-Ji Zhou and Pablo Engel, indicate an important biological role for this protein complex in the regulation of B-cell development and activation.
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页码:437 / 442
页数:6
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