A NOVEL HUMAN CDNA WITH A PREDICTED PROTEIN SIMILAR TO LYSYL OXIDASE MAPS TO CHROMOSOME-15Q24-Q25

被引：0
|
作者：
KENYON, K [1 ]
MODI, WS [1 ]
CONTENTE, S [1 ]
FRIEDMAN, RM [1 ]
机构：
[1] NCI,FREDERICK CANC RES & DEV CTR,PROGRAM RESOURCES INC DYNCORP,BIOL CARCINOGENESIS & DEV PROGRAM,FREDERICK,MD 21702
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 1993年 / 268卷 / 25期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel human cDNA with a predicted protein homologous to the carboxyl end of lysyl oxidase, an extracellular enzyme involved in the maturation of collagen and elastin, has been isolated. The homology to lysyl oxidase begins exactly at the position of the exon 1/exon 2 boundary in the mouse gene (Contente, S., Csiszar, K., Kenyon, K., and Friedman, R. M. (1993) Genomics 16, 395-400). This lysyl oxidase-like gene, which appears to be no larger than 22.1 kilobases, codes for a single poly-adenylated RNA species of 2.48 kilobases and has been mapped to chromosome 15q24-q25.
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页码：18435 / 18437
页数：3
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