SYNTHESIS OF METHYL 2,6-DIDEOXY-4-THIO-ALPHA-D-RIBO-HEXOPYRANOSIDE (METHYL 4-THIODIGITOXOSIDE) - A CONSTITUENT OF THE CALICHEAMICINS AND ESPERAMICINS

被引：0
|
作者：
CLASSEN, A
SCHARF, HD
机构：
来源：
LIEBIGS ANNALEN DER CHEMIE | 1993年 / 02期
关键词：
HEMITHIOACETALS; DEOXY; CALICHEAMICINS; ESPERAMICINS; THIODIGITOXOSIDE; DIGITOXOSIDE; 4-THIO-; ANTIBIOTICS; ANTITUMOR; ANTITUMOR ANTIBIOTICS; SACCHARIDES; CARBOHYDRATES;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The 4-thio analog of 2,6-dideoxy-D-ribo-hexopyranose (D-digitoxose) is part of the saccharide chain of the calicheamicins and esperamicins. A straightforeward synthesis of the 4-thiodigitoxoside 12 as its diacetate 13 starting from methyl alpha-D-galactopyranoside (1) is described. Properties and structure of 13 are presented.
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页码：183 / 187
页数：5
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