SYNTHESIS OF METHYL 2,6-DIDEOXY-4-THIO-ALPHA-D-RIBO-HEXOPYRANOSIDE (METHYL 4-THIODIGITOXOSIDE) - A CONSTITUENT OF THE CALICHEAMICINS AND ESPERAMICINS

被引：0

作者：

CLASSEN, A

SCHARF, HD

机构：

来源：

LIEBIGS ANNALEN DER CHEMIE | 1993年 / 02期

关键词：

HEMITHIOACETALS; DEOXY; CALICHEAMICINS; ESPERAMICINS; THIODIGITOXOSIDE; DIGITOXOSIDE; 4-THIO-; ANTIBIOTICS; ANTITUMOR; ANTITUMOR ANTIBIOTICS; SACCHARIDES; CARBOHYDRATES;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The 4-thio analog of 2,6-dideoxy-D-ribo-hexopyranose (D-digitoxose) is part of the saccharide chain of the calicheamicins and esperamicins. A straightforeward synthesis of the 4-thiodigitoxoside 12 as its diacetate 13 starting from methyl alpha-D-galactopyranoside (1) is described. Properties and structure of 13 are presented.

引用

页码：183 / 187

页数：5

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