EFFECT OF SURFACTANTS ON THE STABILITY OF MODIFIED EGG-YOLK PHOSPHATIDYL CHOLINE LIPOSOMES

被引：7
|
作者：
ALAMELU, S [1 ]
RAO, KP [1 ]
机构：
[1] CENT LEATHER RES INST,BIOMAT LAB,MADRAS 600020,TAMIL NADU,INDIA
来源：
JOURNAL OF MICROENCAPSULATION | 1990年 / 7卷 / 04期
关键词：
D O I：
10.3109/02652049009040477
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Disintegration by surfactants on egg-yolk phosphatidyl choline (PC) vesicles, stabilized with polycholesteryl methacrylate and carboxy methyl chitosan, was investigated by measuring the amount of marker dye (bromothymol blue) released from the vesicles. In all the studies at pH7.4 anionic and nonionic surfactants caused vesicle disintegration at low concentrations while cationic surfactants produced breakdown of vesicles at high concentrations. It was found that the modified liposomes disintegrated in the following order:. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码：541 / 551
页数：11
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