A KINETIC METHOD FOR THE DETERMINATION OF CARBIMAZOLE IN PHARMACEUTICAL PREPARATIONS BY OXIDATION WITH DICHROMATE IN SULFURIC-ACID

被引：9
|
作者：
SULTAN, SM
机构：
[1] Chemistry Department, College of Science, King Fahd University for Petroleum and Minerals, Dhahran, Kfupm Box 2026
来源：
ANALYTICAL SCIENCES | 1992年 / 8卷 / 04期
关键词：
CARBIMAZOLE; POTASSIUM DICHROMATE; FIXED TIME METHOD; KINETICS; SPECTROPHOTOMETRY;
D O I：
10.2116/analsci.8.503
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple spectrophotometric method is introduced for the determination of carbimazole in drug formulation. The method requires the use of 16 mg ml-1 potassium dichromate, 0.5 M sulfuric acid and heating at 90-degrees-C for 25 min. The method is easily applied to the determination of carbimazole in tablet formulations. The accuracy of the method was tested by a statistical comparison with the British Pharmacopeia official method.
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页码：503 / 506
页数：4
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