AMINOGLUTETHIMIDE IN MALIGNANT-MELANOMA A PHASE-II STUDY

被引：4

作者：

BLOCK, S ^{[1
]}

BONNETERRE, J ^{[1
]}

ADENIS, A ^{[1
]}

PION, JM ^{[1
]}

DEMAILLE, A ^{[1
]}

机构：

[1] CTR OSCAR LAMBRET,BP 307,F-59020 LILLE,FRANCE

来源：

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 1992年 / 15卷 / 03期

关键词：

AMINOGLUTETHIMIDE; MELANOMA; ANTIAROMATASE;

D O I：

10.1097/00000421-199206000-00016

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The role of steroid hormones has been suggested in the growth of malignant melanoma, and since aromatase activity has been found in melanoma tissue, we carried out a phase II study of aminoglutethimide, an aromatase inhibitor in malignant melanoma patients. Fifteen heavily pretreated patients entered the study. No response was observed-the treatment was well tolerated. We concluded that aminoglutethimide is very unlikely to be useful in melanoma patients.

引用

页码：260 / 261

页数：2

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