AMINOGLUTETHIMIDE IN MALIGNANT-MELANOMA A PHASE-II STUDY

被引：4
|
作者：
BLOCK, S [1 ]
BONNETERRE, J [1 ]
ADENIS, A [1 ]
PION, JM [1 ]
DEMAILLE, A [1 ]
机构：
[1] CTR OSCAR LAMBRET,BP 307,F-59020 LILLE,FRANCE
来源：
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 1992年 / 15卷 / 03期
关键词：
AMINOGLUTETHIMIDE; MELANOMA; ANTIAROMATASE;
D O I：
10.1097/00000421-199206000-00016
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The role of steroid hormones has been suggested in the growth of malignant melanoma, and since aromatase activity has been found in melanoma tissue, we carried out a phase II study of aminoglutethimide, an aromatase inhibitor in malignant melanoma patients. Fifteen heavily pretreated patients entered the study. No response was observed-the treatment was well tolerated. We concluded that aminoglutethimide is very unlikely to be useful in melanoma patients.
引用
收藏
页码：260 / 261
页数：2
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